Iba1/AIF-1 Rabbit mAb [ONX8]Cat NO.: A76915

Protein names ：AIF1,G1,IBA1,AIF1_HUMAN,Allograft inflammatory factor 1

UniProtID ：P55008

MASS(da) ：16,703

MW(kDa) ：17 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of Human Iba1/AIF-1

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：THP-1 cells

Function ： Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation..

Tissue specificity ：Detected in T-lymphocytes and peripheral blood mononuclear cells..

Subcellular locationi ：Cytoplasm, cytoskeleton. Cell projection, ruffle membrane,Peripheral membrane protein,Cytoplasmic side. Cell projection, phagocytic cup.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.