support:13376277882 | tech@naturebios.com

PLC-gamma-1 (Y783) Rabbit mAb [2NQC]Cat NO.: A74937

Western blot analysis of extracts from Jurkat cells lysates Pervanadate-treated .using PLC-gamma-1 (Y783) Rabbit mAb [2NQC] at dilution of 1:1000 incubated at 4℃ over night

  • SizePriceIn stock
  • 50ul1060.00库存充足
  • 100ul2088.00库存充足
  • 200ul3098.00库存充足
Order Datasheet

Product information

Protein names :PLCG1,PLC1,PLCG1_HUMAN,1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

UniProtID :P19174

MASS(da) :148,532

MW(kDa) :149 kDa

Form :Liquid

Purification :Protein A purification

Host :Rabbit

Isotype :IgG

sensitivity :Endogenous

Reactivity :Human,Mouse

  • ApplicationDilution
  • 免疫印迹(WB)1:1000-2000
  • 免疫荧光(ICC/IF)1:100,
  • The optimal dilutions should be determined by the end user

Specificity :Antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues around Tyr783 of Human PLC-gamma-1 .

Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected :Jurkat cells lysates Pervanadate-treated

Function : Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Plays a role in actin reorganization and cell migration (PubMed:17229814)..

Subcellular locationi :Cell projection, lamellipodium. Cell projection, ruffle.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.