MAP3K4 Rabbit mAb [17Q1]Cat NO.: A83846

Protein names ：MAP3K4,KIAA0213,MAPKKK4,MEKK4,MTK1,M3K4_HUMAN,Mitogen-activated protein kinase kinase kinase 4

UniProtID ：Q9Y6R4

MASS(da) ：181,685

MW(kDa) ：200 kda

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100,
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of Human MAP3K4.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：293  cells lyastes

Function ： Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6..

Tissue specificity ：Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues..

Subcellular locationi ：Cytoplasm, perinuclear region.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.